Mycosis Fungoides Essay -- Biology, T Cells

Mycosis fungoides is a main sub cause of a cutaneous T cell lymphoma (CTCL), in which a heterogeneous parade of lymphomas develop into malignant tummycer cells, primarily affecting the shinny. This unhealthiness can be distinguished from other cutaneous T cell lymphomas by its unique clinical and histologic features (Armitage et al., 2010). Mycosis fungoides can be do by some(prenominal) different ways and is dependent on several factors much(prenominal) as the stage of the cancer, health of the patient, presenting symptoms and patient-specific issues (Parker & Bradley, 2006). Traditional therapies for mycosis fungoides involved radiotherapy therapy, oral psoralen with UVA light therapy and narrow- and broadband UVB light therapy. Recently, novel therapies have been set up to treat CTCL and several of them be starting to become routine therapies for the erythrodermic subgroup of mycosis fungoides. This paper will discuss the historical background of the disease as well as t he new techniques that have been used within the former(prenominal) few years and the traditional methods of treatment.T cells are genetically on the watch to protect and survey the human body from any environmental stressors, contrasted agents and malignancy. Some of these T cells are programmed to protect the skin. Once the body is defile with T lymphocytes, the T cells infiltrate the skin, work together to eradicate the allergen and at long last they undergo the process of natural cell death. However, when specific skin-homing T lymphocytes infect the skin, they then clonally expand and are sometimes unable to exit the skin compartment. Once the lymphocytes accumulate within the skin, the reaction is then known as a rash. This proliferation of abnormal cloning of T cells within the skin distinguishes ... ...ter researching mycosis fungoides, I have learned that the cause of this disease is unknown and unless spy at an early stage, it is approximately likely not curable. What are aureate for patients with mycosis fungoides are the numerous therapeutic options which I find to be remarkable. Since the treatment options are mainly palliative, I have realized the goals of therapy for this disease are symptom relief and consideration for their quality of life. Although most techniques are chosen based upon clinical stage of the disease, what I find most promising is total skin electron beam radiation therapy. With this type of technology being around for several years, and continuously updating to ripe techniques, I find it most beneficial to patients. However, there are several options available for patients and being able to combine different therapies is in their favor.